I tested a 1200 GS WC and an S1000XR today, and absolutely loved them both. They both had the quick shifter on, I thought it was a fantastic gizmo and would definitely have it on any bike in the future. I rode the GS first and was blown away by how fast it was after getting off my 09 800 GS, the engine was bloody brilliant!
Then I rode the XR, and had to of course recalibrate what I thought was fast - holy shit!!! It was a hoot to ride, but I found it slightly cramped after the GS, and my dodgy knees and hip couldn't live with one in the real world - plus I think I'd either get banned or fire myself into a hedgerow somewhere!
Like others have said, it'd have to be the GS for a real world day to day ride, tho if I could afford both, I'd love an XR in my garage for blast out fun!!