Bike wheels being narrower than cars will not as a rule wobble the steering (for the front - left to right). That leaves a center line ballance issue. If it is not too great then the suspension will take most or the vibes that the rider would feel unless of course it is massive, which with todays manufacturing methods is unlikely.
As has been said, manufacturers mark the heavy spot on their tyres and this is so that the tyre is placed on the rim with the heavy bit opposite the valve.
The problem is the bearings. They are designed to roll over each other and the rollers/balls distribute the weight relatively evenly, but they are not designed for the constant hammering from an unballanced wheel.
As has been said, if the imballance is 0.8kg (and I have not worked it out) and the circumference of the wheel is about 2m then at 100mph the bearing is getting shunted up and down about 80,000 times per hour that is not needed.
If you transfer that to a years riding of 12,000 miles then that is multiplied up to a mad figure (albeit not all at 100mph) but....
Could this be the cause of rear wheel bearing failure at 30k miles or whatever ?