I had a 21 inch front wheel fitted to my R1150GS ADV. It replaced the standard 19inch wheel. I did a few off road weekends throughout Europe. I often wondered what the difference would be with a larger wheel. I had seen this conversion before in the Netherlands.
I found the 21 inch front wheel much smoother than the 19 inch over all rough ground and very big holes. It also seemed more forgiving on very soft muddy ground and sand. The hub was an original new R1150GS hub with a new BMW 21 inch BEHR rim professionally built around it by Devon Rim Company. The bearings for the hub were pressed in by my BMW dealer. It had a tubeless TKC80 tyre fitted.
My bike had ABS, the sensor ring fitted onto hub via the brake discs as on the 19 inch hub, you just swap them over. I hope this helps. I have since sold the GS and ordered a BMW HP2, this has a 21 inch front wheel.